proteasome|proteasomes in English
noun
cluster of multi-protein complex
Use "proteasome|proteasomes" in a sentence
1. 19 Ubiquitin - proteasome pathway is a highly effective protein - degradation pathway in the eukaryotic cells.
2. Appraising the roles of CBLL1 and the ubiquitin/proteasome system for flavivirus entry and replication J Virol
3. Additional research is needed to Characterize more fully the role of proteasomes in acute human responses to air pollution
4. Assays for compound screening to inhibit the proteasome and deubiquitinases are offered by Reaction Biology with fluorescent-based activity Assays
5. In another embodiment an injection catheter for delivery an anti-restenotic effective amount of proteasome inhibitor to the adventitia is provided.
6. Anaphase-promoting complex (also called the cyclosome or APC/C) is an E3 ubiquitin ligase that marks target cell cycle proteins for degradation by the 26S proteasome
7. Argyrins, a family of natural products, were identified as potential anti-cancer agents that directly inhibit proteasome activity, which is often aberrantly regulated in cancer.
8. Project members used biochemical techniques to analyse the structural integrity, proteolytic activity and subunit reactions of the affinity-isolated and labelled proteasomes, which were then used to perform single particle CEM analysis.
9. In a particular embodiment, the invention provides a method for determining whether a subject with multiple myeloma is likely to respond to a treatment with a proteasome inhibitor wherein the method comprises the step of performing, on a sample from the subject, a gene expression analysis of a number of N genes selected from the group consisting of the genes NUAK1, ITGB7, AGMAT, TFAP2C, CCDC85A, CLEC7A, TMEM37, RNF144A, and CMPK2, wherein N is at least 2and wherein it is concluded that the subject is likely to respond to a treatment with a proteasome inhibitor in case that at least 2 of said N genes are aberrantly expressed.